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Your microbiome was shaped by your biology. Not a protocol-grade formula.
The Biological Tax Report is a free, six-page research report on why biology determines your microbiome composition more than diet, age, or lifestyle — and what that means for your health. No wellness pitch. Just the published data.
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"Nobody built a probiotic for people like us. So I built one engineered for the biological tax of modern life."
— Gurkamal, Founder
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Cited: Nature Medicine · Cell · Gut
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What's Inside
Six pages. Five findings. A category the industry hasn't built.
This report distils published research from Nature Medicine, Cell, and the AAPS PharmSciTech into a single, readable brief. No product pitch — just the data that led us to build Origin.
The Depletion Problem
The HELIUS study (n=2,084) found biology determines microbiome composition more than diet, age, sex, or medical history — combined. What that means for your biology.
The Biological Tax Report
What happens to your microbiome when traditional diets change — and why depletion compounds across generations rather than stabilising.
The Delivery Problem
Most probiotic bacteria are destroyed by stomach acid before reaching where they work. Why the number on the bottle is measured at manufacture — not at delivery.
The Origin Solution
Why environmental adaptation matters for supplementation, and how Origin uses MAKTREK Bi-Pass Technology + FOS prebiotic to solve both the depletion and the delivery problem.
The Four Strains
L. acidophilus, B. lactis, L. plantarum, L. paracasei — why these four strains were selected to address the specific systems that depletion hits hardest.
"Biology contributed more to explaining interindividual differences in microbiota composition than any other measured factor — including diet, age, sex, or medical history."
Deschasaux et al. — Nature Medicine, 2018 · HELIUS Cohort · n=2,084
Cited in the report
Cell, 2018
Vangay et al. — environmental shift-driven microbiome depletion across generations
View Study →AAPS PharmSciTech, 2014
Govender et al. — Probiotic survivability and acid-protected delivery
View Study →From the Founder
Why I built this company — and why this report is free.
"I didn't set out to build a supplement company. I set out to answer a question nobody was asking: why is the probiotic industry ignoring the biology of the people who need it most?"
I grew up in a Punjabi household in Canada. Daal, roti, achaar, lassi — the foods my family had eaten for generations. But I watched my parents and their friends struggle with digestive issues that nobody could explain. The doctors said "eat more fibre" or "try a probiotic." So they did. Nothing worked.
Years later, I found the research. The HELIUS study. Vangay. The data was clear: when you move to a Western country, your foundational microbiome starts to collapse. Within a single generation. And nobody in the supplement industry was building for that.
Every probiotic on the shelf was formulated for the same generic Western biology. Same strains. Same delivery. Same failure rate. Meanwhile, modern populations across the world were losing the bacterial ecosystems their ancestors spent thousands of years cultivating.
That's why this report is free. Because the science matters more than the sale. And if you read it and decide Origin isn't for you, you'll still understand your biology better than 99% of people who take a probiotic.
— Gurkamal, Founder · BaseCode Health
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